CLIVE SVENDSEN

Ph.D., Director, Regenerative Medicine Institute, Cedars-Sinai Medical Center

Dr. Clive Svendsen is Director of the Cedars-Sinai Regenerative Medicine Institute, Professor in Residence at UCLA and Consulting Professor at Stanford University. He did his pre-doctoral training at Harvard University and received his PhD from the University of Cambridge in England, where he then established a stem cell research group before moving to the University of Wisconsin in 2000 to become Professor of Neurology and Anatomy, Director of an NIH-funded Stem Cell Training Program and Co-Director of the University of Wisconsin Stem Cell and Regenerative Medicine Center. In 2010 he moved to Los Angeles to establish and direct the Cedars-Sinai Regenerative Medicine Institute that currently has 15 faculty members and approximately 100 staff. Dr. Svendsen has worked with human neural stem cells for over 20 years - showing that they can survive and integrate into the brains of many different animal models of disease, including ALS, Parkinson's, Huntington's and stroke.

 

Personalized Medicine Using iPSCs and Organs-on-Chips

We have combined induced pluripotent cell technology with microfluidic chips from Emulate to create “disease-on-chips”.    Using these miniature human systems we have created new models of Crohn’s disease and are developing a complete individualized human blood brain barrier that will predict how novel drugs will be taken up into the human brain.

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