CRISTIAN IONESCU-ZANETTI

Ph.D., CTO, Fluxion Biosciences

Dr. Ionescu-Zanetti is the Chief Technology Officer and co-founder of Fluxion Biosciences. In this role, he is in charge of innovation and product development and has brought Fluxion’s discovery platforms from concept to product. Fluxion’s three assays are used in a range of pre-clinical drug discovery, clinical research and diagnostic applications. Cristian received his Ph.D. in Biophysics from UC Santa Cruz.

Fluxion’s Liquid Biopsy Solution

We present a liquid biopsy approach based on CTC enrichment that results in tumor cell purities above 10%.  Coupled with a high sensitivity NGS bioinformatics workflow, it enables the effective use of standard amplicon panels to detect somatic mutations present in only a handful of tumor cells. Clinical data from urological cancer pilot studies demonstrates robust detection of somatic mutations.

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