M.D., Vice President, Medical and Scientific Affairs, Crescendo Bioscience

Dr. Sasso joined Crescendo Bioscience in September 2012. He came to Crescendo from Abbott Laboratories, where as Medical Director, he worked in Early Immunology clinical development and in Humira Medical Affairs, both in Rheumatology and as head of the Dermatology team. Prior to joining Abbott in 2004, he was Associate Professor at the University of Washington, Seattle, where he has remained an Adjunct Associate Professor since 2004. Dr. Sasso earned an A.B. Biochemistry degree at Harvard University, Cambridge, MA, and an M.D. degree from the University of California, San Diego. He trained in internal medicine at McGill University, Montreal, and did fellowships in rheumatology at the University of Washington, and in immunology research at the Virginia Mason Research Center, Seattle. He is board certified in Internal Medicine and Rheumatology and has published extensively in the fields of rheumatology, immunology and dermatology.


Session: Rheumatoid Arthritis (RA) Biomarkers

Rheumatoid arthritis (RA) is a phenotypically heterogeneous autoimmune disease causing chronic inflammation of synovial tissue. RA typically requires lifelong treatment with close monitoring of disease activity to prevent irreversible joint damage and physical disability. However, there is no precedent for biomarkers in inflammatory disease and there are currently no personalized treatments in RA. This panel of innovators in the field addresses the outstanding questions for understanding the pathobiology of RA, the work that has been accomplished toward identifying biomarkers and the areas that they are currently pursuing to fill the voids. Additionally, the currently available Vectra DA, multi-biomarker blood test that measures RA disease activity to help monitor patients during treatment and evaluate their risk for future joint damage, will be discussed.

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