M.D., Ph.D., Chairman & Professor, Dept. of Cancer Biology, MD Anderson
In 2015, Kalluri’s lab at MD Anderson received widespread attention for a discovery that could lead to a blood test that detects pancreatic cancer at an early stage, before it spreads to other organs and becomes too difficult to treat. Kalluri received his PhD in Biochemistry and Molecular Biology from the University of Kansas Medical Center and his M.D. degree from Brown University Medical School. In 1997, he moved to Harvard Medical School as an assistant professor of medicine and as a faculty based in the Department of Medicine at the Beth Israel Deaconess Medical Center. Subsequently, Kalluri was appointed the chief of the Division of Matrix Biology and promoted to professor of medicine at Harvard Medical School.
Utility Of Exosomes in the Detection of Cancer
Exosomes are proteins and nucleic acids containing vesicles secreted by all cells and are found circulating in the blood. Isolation of cancer-cell-specific exosomes has been found to be indicative of even early stage cancer. These may thus serve as a potential non-invasive diagnostic and screening tool to detect early stages of pancreatic and other cancers.